SR 211 begins at an intersection with US 29/SR 8/SR 316 (University Parkway) in Statham, in Barrow County.

It curves to the west to meet SR 11 (Jefferson Highway), northeast of Winder.

Just after entering town, SR 53 (Gainesville Highway) joins the concurrency.

A short distance later, the route cuts across the northernmost corner of Gwinnett County and intersects SR 347 (Thompson Mill Road NE).

It enters Hall County and heads northwest and curves to the north until it meets SR 53 (Winder Highway) again.