After arcing to the northeast past Chattahoochee Technical College's main campus, Georgia 5 departs the concurrency at Atlanta Road.

Georgia 280 then curves to the southeast, passing through Dobbins Air Reserve Base, and then to the east to an intersection with U.S. 41/Georgia 3 or Cobb Parkway.

[citation needed] Georgia 280 is a major urban arterial, with portions of the route seeing an average annual daily traffic (AADT) of over 30,000 vehicles, especially around Dobbins Air Reserve Base.

It serves as a major commuter route in southern Cobb County and for those traveling to Dobbins Air Reserve Base and the adjacent Lockheed Martin plant in Marietta.

This new bridge was dedicated on August 8, 2012, to Georgia State Patrol Trooper First Class Chadwick “Chad” LeCroy, who was killed in the line of duty in December 2010.