Prespakis was selected in the 2022 AFL Women's season 7 All-Australian team and won the Geelong best and fairest award in 2023.

Prespakis won her second best and fairest award in 2021, scoring seven best-on-ground votes in just nine appearances for the Cannons.

She made her AFL Women's debut in the opening round of 2022 season 6 against North Melbourne at Arden Street Oval, a game in which she was nominated for the 2022 AFL Women's season 6 Rising Star award.

[6] In round 1 of 2022 AFL Women's season 7, Prespakis kicked Geelong's only two goals, including one in the last minute to score a 15–11 victory over Richmond at GMHBA Stadium.

She was voted the Cats Fans MVP and won a new award named the Grit award, where "Cats players voted each week on who they believed showed the most 'grit' during games, throughout acts such as tackles, smothers, intercepts, gut running and pressure acts.