He was educated at the Colegio Nacional de Monserrat and graduated in civil law in 1796 at the University of San Carlos, both in Córdoba.

[1] Salguero was Finance Minister (Ministro de Hacienda) in the provincial government of José Javier Díaz.

He was, along with his Córdoba colleagues, among the few federalists in the Congress, speaking for a system of strong autonomous provinces.

[2] In 1819, Salguero was appointed Treasurer of the Casa de la Moneda (mint) of Buenos Aires.

[3] A street in the Palermo district of Buenos Aires, Jerónimo Salguero, is named after him.