She has produced multiple documentary and narrative films focusing on social justice issues including The Invisible War (2012), The Square (2013), The Hunting Ground (2015), Won't You Be My Neighbor?
[2] Dreyfous is the chair and co-founder of the Utah Film Center, which provides funding to filmmakers.
[3][4] In 2007, Dreyfous co-founded Impact Partners, a documentary production company alongside Dan Cogan.
[8] Including Born into Brothels (2005) directed by Zana Briski and Ross Kauffman, which won the Academy Award for Best Documentary Feature.
[17][18][19] In 2021, Dreyfous was nominated for a Peabody Award as one of the executive producers of the docuseries Nuclear Family.