Germanus IV of Constantinople (Greek: Γερμανός; 1788 – 16 September 1853) served two terms as Ecumenical Patriarch of Constantinople, from 1842 to 1845 and from 1852 until his death on 16 September 1853.

He was elected to the patriarchal throne for the first time in 1842 and held the post until 1845 when he was succeeded by Meletius III of Constantinople.

Restored to the throne in 1852, he occupied it until his death the next year.

His name was particularly associated with the education of the Orthodox clergy, as he was the founder of the Theological School of Halki in the monastery of the Holy Trinity.

The school operated regularly until 1971 when it was closed by law and brought forth many theologists, priests, bishops and patriarchs of note.