Gernrode (German pronunciation: [ɡɛʁnˈʁoːdə] ⓘ) is a historic town and former municipality in the Harz District, in Saxony-Anhalt, Germany.

Gernrode is situated at the northeastern rim of the Harz mountain range and the Harz/Saxony-Anhalt Nature Park, about 6.5 km (4.0 mi) south of Quedlinburg.

It is nationally recognized for its health facilities and has state recognition as a spa town, where one may take the cure and recuperate in general (staatlich anerkannter Kur- und Erholungsort).

In 959 the Saxon margrave Gero founded a convent of canonesses in the Schwabengau territory, within the grounds of the Geronisroth fortification he built about the same time.

Without male heirs, he bequested his vast properties to the convent and made his daughter-in-law Hathui (d. 1014), widow of his son Siegfried, first abbess (r.959-1014).

In 1728 Emperor Charles VI formally enfeoffed the Anhalt princes with Gernode which was incorporated into Anhalt-Bernburg, raised to a duchy in 1806.

Due to its picturesque setting, Gernrode became a popular destination for recreational visitors from the early 19th century onwards.

On 19 April 1945, at the end of World War II, Gernrode was taken by the US Army without a battle, followed by occupation by Soviet troops in June.

Other local attractions include a 7.45 m giant wood thermometer, the largest Skat table in the world, and the Prussia Tower on the Ölbergshöhe.