During the Cold War, Ghanaian President Kwame Nkrumah gradually became affiliated with the Soviet Union following hist ideological turn towards "African socialism" and his confrontation with the Western Bloc in the Congo Crisis.

Nkrumah made a two-month round-trip in the Soviet Union and the Eastern Bloc (including Yugoslavia and China too) in the summer of 1961, during which he visited Hungary from 28 to 31 July.

[3] A Hungarian delegation of economic experts, led by József Bognár, a former Mayor of Budapest, was invited to Ghana to work on the First Seven-Year Plan.

[2] Hungary reopened its embassy in Accra on 1 April 2016 as part of the Orbán government's "Southern Opening" foreign policy program.

[5] The embassy also serves eight other West African countries namely Togo, Burkina Faso, Ivory Coast, Liberia, Guinea, Sierra Leone, Gambia, and Senegal.