The independence ceremony was attended by Mexican Ambassador Eduardo Espinosa y Prieto who previously had been in Ghana a year earlier as UN appointed Commissioner for the 1956 British Togoland status plebiscite.

[2] While in Ghana, Ambassador Espinosa y Prieto met with President Kwame Nkrumah and discussed the establishing diplomatic relations between both nations.

Both officials reviewed the status of the bilateral relationship and discussed multilateral issues such as the reform of the Security Council and follow-up of the Cancun Agreements on climate change.

[4] In December 2018, Foreign Deputy Minister Charles Owiredu arrived in Mexico City to attend the inauguration for Mexican President Andrés Manuel López Obrador.

Mexico's main exports to Ghana include: malt extract and food preparations, alcohol, chemical based products, telephones and mobile phones, frozen or chilled fish, motor cars and other vehicles, tractors, tubes and pipes.