Her paternal grandfather was Mirza Muhammad Madani, who was of either Arab or Turkic descent, the son of a foster-brother of the Mughal emperor Aurangzeb.

[2][4] Ghaseti Begum married her paternal cousin, Nawazish Muhammad Khan, who was the Naib Nazim of Dhaka.

[1] Being childless, the couple adopted Ikram ud-Daulah, the son of her younger sister Amina Begum.

Eventually she secretly conspired against him with the help of Mir Jafar, the chief of Alivardi Khan's army, along with the merchants Omichund and Jagat Seth.

[citation needed] After the fall of Siraj ud-Daulah in the Battle of Plassey in 1757, Ghaseti was imprisoned in the Jinjira Palace by Mir Jafar.