Nearby localities include Kafr Mousa to the south, district capital al-Qusayr 13 kilometers to the southeast, al-Buwaida al-Sharqiya to the east and Qattinah to the northeast.

According to the Syrian Central Bureau of Statistics (CBS), al-Ghassaniya had a population of 4,509 in the 2004 census.

[1] Its inhabitants are predominantly Christians and there is a minority of Murshidiyeen, who are members of a heterodox offshoot of the Alawites.

The village's main source of income is from agriculture and residents mostly grow cabbage and potatoes.

[2] During the Syrian civil war, al-Ghassaniya was besieged by anti-government rebels for roughly eight months between September and May 2013.