The success of Columbia's (unrelated) film spurred Filmation to resurrect their own property, producing an animated series based on the characters from the earlier TV show.

Jake Kong Jr. and Eddie Spenser Jr. are the sons of the original Ghost Busters from the live-action comedy series of the same name; Tracy the Gorilla had worked with their fathers.

Their headquarters, termed Ghost Command, is located in a haunted mansion nestled between a number of tall skyscrapers (which resemble the World Trade Center's Twin Towers in New York City).

They occasionally enlist the aid of Futura, a time-traveling Ghostbuster from the future, and Jessica Wray, a local TV news reporter.

Prime Evil's headquarters, termed the Hauntquarters (which resembles the British Houses of Parliament complete with a Big Ben-esque clock tower), is located in The Fifth Dimension.

In a typical episode, Prime Evil uses his magical powers to open up a wormhole to enable one or more of his henchmen to complete a particular scheme that serves to help him take over the world.

When Columbia Pictures began work on the film Ghostbusters in 1984, producers overlooked the fact that Filmation had already created a live-action comedy series with that same name in 1975.

After the film became a success, Filmation offered to make an animated series, but Columbia chose instead to give the contract to DiC.

The series of figures included Jake, Eddie, Tracy, Belfry, Futura, Jessica, Brat-A-Rat, Prime Evil, Haunter, Scared Stiff, Mysteria, Fib Face and Fangster.

The following were not made into action figures, play sets, and roleplay accessories: Madam Why, Airhead, Flozart, Long John Scarechrome, Sir Trance-A-Lot and Frightmare, Apparatia, the Hauntquarters.

Each episode on BCI Ink & Paint's DVD releases of the 1986 animated series of Filmation's Ghostbusters was uncut, re-mastered and in story continuity order.

In the episode "The Girl Who Cried Vampire", Filmation reused the model sheets and character designs of Drac and Bella La Ghostly from the Groovie Goolies as Victor and Vampra.