Ghosts of the Great Highway is the debut studio album by San Francisco quartet Sun Kil Moon, led by Red House Painters' founder Mark Kozelek, who composed all of the lyrics and music on this album.

The other members are Anthony Koutsos (former drummer for Red House Painters), Geoff Stanfield, and Tim Mooney.

Three of the album's songs are named after boxers, following on from "Find Me, Rubén Olivares" from Kozelek's debut solo EP Rock 'n' Roll Singer.

Ghosts of the Great Highway was re-issued as a double CD on February 6, 2007 on Kozelek's own label, Caldo Verde Records.

The songs "Carry Me Ohio" and "Lily and Parrots" were featured in the film Shopgirl, in which Kozelek made a cameo appearance.