A native of Atlanta, Georgia, Pergolini has attended Florida International University since 2022 where she is a part of the swimming and diving team.

[1][2] Pergolini made her international debut at the 2017 World Para Swimming Championships where she won a silver medal in the 100 metre backstroke S13.

She again represented the United States at the 2019 World Para Swimming Championships where she won a silver medal in the 100 metre backstroke S13.

[3] During the 2018 U.S. Paralympics Swimming Para National Championships, she set the American record in the 100 metre backstroke S13 with a time of 1:07.97.

[4] Pergolini, just 17 years old, competed in the women's 100 metre backstroke S13 event at the 2020 Summer Paralympics where she set a world record with a time of 1:05.05 in the qualifying heats.