H. arizonensis is the largest scorpion in North America,[2] and one of the 8–9 species of Hadrurus in the United States, attaining a length of 14 cm (5.5 in).

Arizona Desert hairy scorpions are a warm-desert species, specially adapted to hot and dry conditions.

They are usually found in and around washes or low-elevation valleys where they dig elaborate burrows (up to 2.5 m or 8 ft 2 in) and emerge at night to forage for prey and mates.

[2] Its competitors include the giant desert centipede which is also a natural predator to the scorpion.

[3] However, an allergic reaction to its venom is uncommon; symptoms can include difficulty breathing, excessive swelling, and prolonged pain.