[2] The game focuses on team-based action combat with heroes battling alongside a massive guardian.

Players control their selected Heroes, which fill the gameplay roles of a shooter, melee fighter, or spellcaster.

Each playable character has 5 skills, which includes their basic attack and their "Focus" ability, which charges as they deal damage, heal others, etc.

Creatures assist the team in different ways but will remain in the area they were spawned and will automatically collect power orbs on their circle.

As players advance towards the goal of killing the enemy Guardian, they progressively gain a total of 10 Skill Points.

For example, the skill of one hero (Tyto the Swift) which allows them to jump forward and cut down a retreating enemy, can be upgraded to either inflict heavy bleeding on their victim, or to remove the attack altogether and greatly increase the skill's jumping distance.

This was intentionally made to be done manually in the original 2017 release and previous beta builds, as developers wanted players to select upgrades in reaction to the trajectory of the session, but Rampage Edition adds the option to craft a "Build" of upgrades for a Hero which are automatically applied as the match progresses.

With the release of 'Gigantic: Rampage Edition' in 2024, the original gameplay model was retroactively reintroduced as "Clash", while a faster paced gamemode called "Rush" was added, where Guardians only have one health bar, arenas begin in their smaller form, all players are automatically max level thanks to the new "Build" mechanic, and creatures are unable to be summoned, rather automatically spawn themselves.