Known for his ability to stickhandle in close quarters, he is regarded as one of the most skillful playmaking centres of all time.

Among his career highlights was the game-winning goal in overtime of the 1978 National Hockey League All-Star Game played at the Buffalo Memorial Auditorium.

In his second season, the team finished first in the OHA and won the 1969 Memorial Cup Canadian Junior championship.

[5] After Houle moved on to become the NHL's first overall pick, Perreault assumed the leadership role and compiled a 51-goal, 71 assist season, which led the team in both categories and place second in the league to Marcel Dionne's 132 points.

[8] The Canadiens defeated the Weyburn Red Wings to become the third junior team to successfully defend their championship and the Memorial Cup.

[2] The record of the 1969 and 1970 Montreal Junior Canadiens in the playoffs was so outstanding it caused a change in Memorial Cup eligibility rules.

[10] Coincidentally, Perreault had worn #11 throughout his junior career, and kept it in Buffalo in honour of the roulette wheel choice.

He scored a goal in the franchise's very first game, which was a 2–1 victory on October 10, 1970, against the Pittsburgh Penguins.

[4] During his first season, he led the Sabres in scoring (with 38 goals and added 34 assists) — a feat he would never fail to accomplish in any season in which he did not miss significant time to injury before his penultimate year — and won the Calder Trophy as rookie of the year.

[11] Perreault developed a reputation as a superb stickhandler,[6] and scored a goal on his first shift in a professional scrimmage.

"[6] Before the 1971–72 NHL season the Sabres drafted Perreault's Junior Canadiens teammate, Rick Martin, with their first pick.

They ended the following 1972–73 season sweeping the top three scoring positions for the team and leading the franchise to its first playoff appearance with Perreault winning the Lady Byng Trophy as the most gentlemanly player.

The Sabres defeated original six teams Chicago Black Hawks and Montreal Canadiens on their way to a Finals appearance against the Philadelphia Flyers.

He was playing some of the best hockey of his career, leading all scorers with nine points in four games, when he was forced out of the tournament with a broken ankle.

Along with the other two members of the French Connection, Perreault was inducted into the Buffalo Sabres Hall of Fame in 1989.

A statue of "The French Connection," unveiled in 2012,[15] is located outside of the Sabres' arena, known today as KeyBank Center.

In addition, he also plays on occasion with the Buffalo Sabres Alumni Hockey Team for charity events.

After retiring from playing, Perreault coached junior ice hockey, and invested in real estate.