Giles Wemmbley-Hogg Goes Off is a BBC Radio 4 comedy written by Marcus Brigstocke, Jeremy Salsby and Graeme Garden, produced by Pozzitive Television.

The show follows the travel adventures of title character Giles Wemmbley-Hogg ("Two Ms, two Gs", full name: Giles Peter St John David Habakkuk St John Wemmbley-Hogg), a nice but somewhat dim upper class former public school boy (Charterhouse) played by co-writer Brigstocke.

Themes in this comedy are Giles's naïveté, and small-mindedness, with his frequent (and usually inappropriate) comparisons with life back in his native Budleigh Salterton.

One of the special features on Brigstocke's 2007 standup DVD Planet Corduroy is a one-man lecture given in character by Giles Wemmbley-Hogg.

After an eight-year gap Giles Wemmbley-Hogg returned for a special Brexit episode broadcast on BBC Radio 4 on 28 March 2019, the day before the United Kingdom was originally due to leave the European Union.