The institution was founded as "Club Cosmopolita de Gimnasia y Esgrima" on 11 November 1880, by fencing and gymnastics enthusiasts in the "Confitería del Aguila", a traditional coffee house of Buenos Aires.

Gimnasia stated that its members should not pay for tickets because of their membership, which allowed them to take part in all the activities, including free access to the stadium.

The conflict persisted until Gimnasia decided to disaffiliate from the Association on July 14, 1912, establishing a new league, the "Federación Argentina de Football", presided by Ricardo Aldao himself.

Other clubs followed Gimnasia y Esgrima joining the new league, such as Porteño, Estudiantes de La Plata, Independiente, and other teams from the second division.

[6] The club's stadium (which has a capacity of 18,000 spectators) was the field where the Argentina national team played its home games since 1910, making its debut during the Copa Centenario Revolución de Mayo held there.

[8] After leaving the official football leagues in the decade of 1920, rugby union was one of the predominant sports of Gimnasia y Esgrima, winning the Torneo de la URBA titles of 1911 and 1912.

[2] Gimnasia has gained a good reputation in women's field hockey due to its successful campaigns during the decade of the 2000, having won 7 Torneo Metropolitano titles, six of them consecutively being the last in 2012.

[10][11] In September 2014, the rugby union senior squad returned to the first division (Grupo I) after defeating Manuel Belgrano by 23–16 at playoffs (Zona Reubicación).