[4] Later, she obtained a Master of Arts degree in romance languages and literatures from Princeton University.

In 2006, Méndez-Miró became assistant attorney general for human resources at the Puerto Rico Department of Justice.

At the department, she provided legal counsel to the attorney general regarding compliance with local and federal employment laws and regulation, litigated charges filed before the U.S.

President Biden nominated Méndez-Miró to the seat vacated by Judge Carmen Consuelo Cerezo, who retired on February 28, 2021.

[12] On January 3, 2023, her nomination was returned to the President under Rule XXXI, Paragraph 6 of the United States Senate; she was renominated later the same day.

[21][22][23] Méndez-Miró is married to Maite Oronoz Rodríguez, chief justice of the Supreme Court of Puerto Rico.