Giovanni Battista De Negri (30 July 1851 – 3 April 1924)[a] was an Italian operatic tenor particularly known for his portrayal of the title roles in Wagner's Tannhäuser and Verdi's Otello.

He made his debut on 26 December 1876 at the Teatro Sociale in Bergamo in Filippo Sangiorgi's opera Diana di Chaverny and the following month appeared there to great success in the title role of Donizetti's Poliuto.

[1] In 1878 De Negri was contracted by the Croatian National Theatre in Zagreb where he sang numerous leading roles in operas by Verdi, Bellini, Donizetti, and Meyerbeer, as well as appearing in the world premiere of Ivan Zajc's Lizinka.

According to Rodolfo Celletti, De Negri may have lacked the ringing tone found in Tamagno's high notes but was superior to him in his diction, phrasing, and acting skills.

[3] By 1896, the assumption of multiple taxing dramatic tenor roles and a frenetic performance schedule took a toll on De Negri's voice.