Banksy has several times used variants of this design to support social campaigns: in 2005 about the West Bank barrier, in 2014 about the Syrian refugee crisis, and also about the 2017 UK election.

[7][8] In addition to the signed and unsigned edition, a series of 88 artist proofs consisting of blue, pink, gold and purple hearts (22 of each colour) were also released.

[10] The artwork motif was also released in 2005 as a series of hand-sprayed paintings comprising multiple versions including a signed diptych edition of 25 with each panel measuring 30 x 30cm.

[15][16] In March 2014, the third anniversary of the Syria conflict, Banksy reworked the painting to depict a Syrian refugee and added the hashtag #WithSyria.

[18] In July 2017, a Samsung poll of 2,000 people from the United Kingdom asked participants to rank twenty pieces of British art.

The offer included a disclaimer: "This print is a souvenir piece of campaign material, it is in no way meant to influence the choices of the electorate.

[24] Moments after the closing bid, the artwork began to self-destruct by means of a hidden mechanical paper shredder that Banksy had built into the frame bottom.

[31] A print of Girl with Balloon, worth an estimated £270,000, was stolen from the Grove Gallery in New Cavendish Street, London, in September 2024.