"[13] Brian Lowry, writing for Variety, applauded the series' cast and material, noting how it sticks to the network's demographic while maintaining a level of quality.

[14] Gail Pennington of St. Louis Post-Dispatch called the series "a smart, solid examination of just how messy relationships are and how hard it is to make them work.

"[15] Slate's Willa Paskin highlighted Edelstein's portrayal of the lead character, describing her as "very well cast, both commanding and nurturing enough to seem like the ideal advice-giver" and noted that the series has "a satisfying and complex take on social dynamics in friendship and romance.

"[16] Alessandra Stanley of The New York Times praised Edelstein and Garofalo as "one reason" the show is entertaining and found the comic side of the series "a lot more fun.

"[17] Time's writer James Poniewozik praised the writing and Edelstein's "sympathetic" performance, noting that the latter "grounds a show that often otherwise plays like young-adult fiction for actual adults."

However, Poniewozik opined that "there's one lesson Girlfriends’ Guide to Divorce has (over)learned from its Bravo peers: that there's no reality so compelling that it can’t be sweetened with a little Photoshop.

"[18] David Hinckley, writing for the New York Daily News, highlighted the series' best moments as those showing the messy side of marital discourse while heralding Edelstein's performance as "memorably moving.