Giuseppe Milesi Pironi Ferretti (9 March 1817 – 2 August 1873) was an Italian Catholic cardinal and politician of the Holy See.

Ferretti was born on 9 March 1817 in Ancona and was educated there until he joined the Pontifical Academy of Ecclesiastical Nobles.

[1] He was appointed Catholic Church governor of Ascoli, then Civitavecchia and finally Macerata.

He served as pro-legate in both Urbino and Forlì until his appointment as minister of Commerce, Fine Arts and Public Works of the Papal States in 1854.

He served as camerlengo of the Sacred College of Cardinals from 1869 to 1870 and participated in the First Vatican Council.