Giuseppe Mulè (28 June 1885, Termini Imerese - 10 September 1951, Rome) was an Italian composer and conductor.
In 1903, even before completing his academic studies, he composed a Largo for cello and piano that was used as an opening song in national radio broadcasts in Italy for RAI.
After graduating from the conservatory he pursued a career as a conductor in Italy, working with many of that nation's leading orchestras.
He left there in 1925 to become the director of the Accademia Nazionale di Santa Cecilia, a post he held for 20 years.
He was made national secretary of the Sindicato del Musicisti, which he represented in parliament alongside composer Adriano Lualdi from 1929 on.