"Give It Up, Turn It Loose" is a song by American R&B/pop vocal group En Vogue, released as the fourth single from their second album, Funky Divas (1992).

"[5] Randy Clark from Cash Box stated, "Although they use the same basic sound and style, these Funky Divas have opted for a more smooth and kicked back approach on this track, compared to their current spirited hit single, with an over-all vibe that's slightly reminiscent of Cheryl Lynn's 'Got to Be Real'.

"[6] John Martinucci from the Gavin Report found that "Maxine and the girls are giving some sisterly advice for those who are stuck in dead end relationships", calling it a "down-tempo track".

"[13] Cheo H. Coker from Stanford Daily named it "perhaps the most enjoyable on the album; the jam is the catchiest thing since its Debarge predecessor, 'I Like It', from which it takes its inspiration.

"[14] The accompanying music video for "Give It Up, Turn It Loose" was directed by German feature film director and producer Marcus Nispel.