Gladstone is an unincorporated layover in Union County, New Mexico, United States, founded in 1880.

The post office, which opened in 1888, closed in 2010, leaving only a general store with gas service, and two houses, located there.

The rest of the community has reverted to private ranch land.

[3] He named it in honor of William Ewart Gladstone, a Liberal politician and the British Prime Minister at the time.

A fair number of settlers came to Gladstone, but many left disillusioned shortly thereafter.