The initial band line-up was completed by Rob Chapman (singer) joining in November 1977, and their first gig was held just 3 weeks later in The Dockland Settlement, St Pauls, Bristol.

For this release the band had been forced by pharmaceutical company Glaxo to change their name, and this resulted in the use of "Gl*xo Babies", with an asterisk replacing the "a", although subsequent recordings have used a mixture of the two forms.

Tony Wrafter (saxophone) had joined the band in early 1979, and in May 1979 drummer Geoff Alsopp was replaced by Welshman Charlie Llewellin.

However, due to artistic differences Rob Chapman promptly left the group after the recording of just a couple of run through tracks (including a song about Christine Keeler, former Prime Minister Harold Macmillan and the political scandal known as the Profumo affair).

Following the abrupt departure of Rob Chapman the other four members, supplemented by Tim Aylett (and later Alan Jones), took the band "into a more experimental area, leaning more towards a free-form fusion of jazz and dance rhythms",[3] which resulted in them recording, in one day, the album Nine Months to the Disco.

Heartbeats final Glaxos' release was a compilation album of early demos and unreleased tracks from the Rob Chapman period, called "Put Me on the Guest List".

The band (Rob Chapman, Dan Catsis and Charlie Llewellin) reconvened in the summer of 1985, and continued to record sporadically until they finally disbanded in 1990.