Its major stores are Target, Lowe's, Landmark Theatres, and a branch of the Indianapolis Public Library.

Representatives of the William H. Block Co. chain said that they felt that the location was suitably positioned for the city's growth at the time, and that having both department stores in the same center would offer a greater shopping variety for customers.

Until Glendale's construction, most major department stores in Indianapolis were located only in the Downtown district.

Glendale was frequently the first local branch store away from the established flagship locations downtown.

Following the opening of The Fashion Mall at Keystone two miles (3.2 km) north, Glendale began to lose many of its better-known tenants.