Glendenning is a suburb of Sydney, in the state of New South Wales, Australia.

Glendenning is located 44 kilometres west of the Sydney central business district, in the local government area of the City of Blacktown and is part of the Greater Western Sydney region.

Aboriginal and Torres Strait Islander people made up 2.7% of the population.

The next most common countries of birth were India 13.1%, Philippines 12.3%, Fiji 2.7%, New Zealand 2.3% and Pakistan 1.5%.

Other languages spoken at home included Punjabi 11.8%, Tagalog 8.1%, Hindi 3.8%, Filipino 3.2% and Arabic 2.6%.