Gmina Dobrzeń Wielki, German Gemeinde Groß Döbern is a rural gmina (administrative district) in Opole County, Opole Voivodeship, in south-western Poland.

Its seat is the village of Dobrzeń Wielki, which lies approximately 13 kilometres (8 mi) north-west of the regional capital Opole.

The gmina covers an area of 91.42 square kilometres (35.3 sq mi), and as of 2019 its total population is 9,457.

The gmina contains part of the protected area called Stobrawa Landscape Park.

Gmina Dobrzeń Wielki is twinned with two other towns, these being: