Gmina Zagórz is an urban-rural gmina (administrative district) in Sanok County, Subcarpathian Voivodeship, in south-eastern Poland.

Its seat is the town of Zagórz, which lies approximately 6 kilometres (4 mi) south-east of Sanok and 61 km (38 mi) south of the regional capital Rzeszów.

Ethnically the population of the region includes Poles and Pogorzans.

The gmina contains part of the protected area called Cisna-Wetlina Landscape Park.

Apart from the town of Zagórz, Gmina Zagórz contains the villages and settlements of Brzozowiec, Czaszyn, Kalnica, Łukowe, Mokre, Morochów, Olchowa, Poraż, Średnie Wielkie, Tarnawa Dolna, Tarnawa Górna and Zahutyń.