In 1933, along with his great friend Kitani Minoru, Go Seigen developed and popularized the Shinfuseki that broke away from the traditional opening patterns.

Go Seigen had only two formal disciples—Rin Kaiho, Honorary Tengen[5] and Rui Naiwei, who was the strongest female go player ever and won open Guksu title.

The accident marked the beginning of the end for Go Seigen's career, as he was unable to play effectively in grueling long matches due to nausea and dizziness.

He authored a number of books on go, some of which include A Way of Play for the 21st Century, Modern Joseki Application Dictionary, and Fuseki and Middle-game Attack and Defense.

Go Seigen held study sessions with other professional players such as O Rissei, Michael Redmond, Rui Naiwei, and others.

In 1987, Go Seigen was awarded the Grand Cordon of the Order of the Rising Sun, 3rd Class, Gold Rays with Neck Ribbon, for his lifetime contributions to Go.

"[6] In the early morning of 30 November 2014, Go Seigen died of natural causes at a hospital in Odawara, Kanagawa Prefecture, Japan, at the age of 100.

Some of the defeated were Kitani Minoru, Karigane Junichi, Hashimoto Utaro, Iwamoto Kaoru, Fujisawa Hosai, Sakata Eio, and Takagawa Kaku.

Some ten years later, Go Seigen took revenge on Fujisawa by beating him in two consecutive jubango with lopsided scores of 7–2 and 5–1 respectively.

[4] Go Seigen was notable for his fast-paced development and playing, fighting style, positional judgment and accurate reading.

[5] In addition to being a peerless match player, Go Seigen has also made great contributions to go theory, especially in the area of fuseki.

He is well known, along with Kitani Minoru, as one of the two leading exponents and innovators of the shinfuseki, a period of revolutionary experimentation in the opening of the game that broke away from traditional moves.

[5] During the 1950s, apart from playing the jubango, Go Seigen participated in many three-game special matches against the Honinbo title holders and other notable players.

His opponents in these matches included many illustrious names, such as Hashimoto Utaro, Sakata Eio, Takagawa Shukaku, and the ex-Honinbo Iwamoto Kaoru.

[4] In 1933, Go Seigen won a special Nihon Ki-in tournament to have the opportunity to play a game against Honinbo Shusai Meijin.

[5] Five years later in 1938, Go Seigen's great friend Kitani Minoru also played a notable game against Honinbo Shusai (see The Master of Go by Yasunari Kawabata).

Due in no small part to having witnessed the treatment Go Seigen received from Shusai in their previous match, Kitani Minoru demanded that the moves be sealed before each adjournment.

[5] In 2006, Chinese director Tian Zhuangzhuang made an award-winning biopic film about him entitled The Go Master, starring Taiwanese actor Chang Chen as Go Seigen.

The film marked the 10th anniversary of the establishment of diplomatic ties between Japan and the People's Republic of China.

Go was often not allowed or invited to participate in the Japanese tournaments of the day due to political reasons involving his racial background.