The majority is told in flashback and shows a past quest for the Ambrosia of Asclepius, and also relates the story of Kratos' present search for the same object.

The comic book series was announced at the 2009 Comic-Con International, and was scheduled to debut in October 2009, but its launch was delayed to coincide with that of God of War III in March 2010.

[2][3] In an interview with Comic Book Resources, Wolfman stated that Santa Monica suggested the use of two time periods, with past events affecting the narrative present.

[13] In the present, Kratos encounters his ally and mentor Athena, the Goddess of Wisdom,[14] and the Chaos Giant, Gyges.

[25] After taking that position himself, Kratos sets out on a quest to destroy the legendary Ambrosia of Asclepius, an elixir with magical healing properties that he once found when he was a soldier in Sparta.

During his quest, Kratos has flashbacks to this period, as he searches for the Ambrosia to save his newly-born daughter, Calliope, who is suffering from the plague.

Each will choose a champion who is in search of the Ambrosia, with the successful god receiving an award (e.g., having statues erected in their honor across Greece).

After being almost burned alive, Kratos drowns his foe and successfully retrieves the Ambrosia, but as he leaves, he and his Spartan troops are ambushed by Alrik's horde of barbarians.

Alrik uses the head of Danaus to summon rocs to attack Kratos as he flies away on a similar bird with the stolen Ambrosia.

[31] Bitter at having lost the wager, Hades resurrects Alrik, who becomes King after his father dies and swears vengeance against Kratos.

[32] In the present, Kratos overcomes several obstacles in his quest to find the Ambrosia, including defeating a giant spider,[33] ignoring Athena's pleas to stop his quest, and overcoming the reanimated corpses of Captain Nikos and his men—a final attempt by Hades to stop the Spartan.

An outraged Gyges explains that Kratos had thwarted the Giant's plan to use the elixir to resurrect his brothers Briareus and Cottus, and then reclaim the world.

In his fiery battle with Cereyon, Kratos inadvertently burned off Gyges' one hundred arms, and then stole the Ambrosia.

During the battle, Kratos reveals that he seeks to destroy the elixir to prevent the worshipers of the slain god Ares from resurrecting their master.

Mike Murphy of Platform Nation stated that although the comic series serves as a good prequel to the video game series, "the story is bogged down by horrible art...[it's] muddy, confusing, and consistently pulls you out of the story as you try to figure out just what is going on from panel to panel."

The reviewer stated that the idea of Kratos finding the Ambrosia to save Calliope was a "perfect comic book incentive," however, things started to disintegrate when the distinction between the present and the past became unclear.

[38] A four out of five star review from Binary Messiah praised the comic series, saying that it could be made into a full game: "That's one freaking awesome story.