The fourth season of the Golden Kamuy anime television series is based on Satoru Noda's manga series of the same name and adapts from the 21st volume to the beginning of the 25th volume (chapters 171–172; 201–244).

In December 2021, it was announced that the anime series would receive a fourth season.

Brain's Base produced the season, replacing Geno Studio.

[3] The opening theme is "Never Say Goodbye", performed by ALI featuring Mummy-D, while the ending theme is "Subete ga Soko ni Arimasu You Ni", which is performed by The Spellbound.

[4] On November 7, 2022, it was announced that the season's broadcast from episode 7 and beyond would be postponed following the unexpected death of a main production staff member.