A filly, Goldikova won a total of 14 Group One races in her home country, Great Britain and the United States, with nine victories over male horses.

She started with two seconds and a third and loss to Zarkava (in the Poule d'Essai des Pouliches and the Prix de Diane), then had three consecutive wins.

[7] Goldikova's third straight victory of the year came in September at Longchamp Racecourse in the Group One Prix du Moulin in which she defeated Darjina and Natagora again as well as top Irish colt Henrythenavigator.

She again defeated the males in winning the 2008 Breeders' Cup Mile at Santa Anita Park in California and was a finalist for the Eclipse Award's American Champion Female Turf Horse for 2008.

At the same Deauville course on 16 August, Goldikova won her sixth group one race, easily defeating her male counterparts in the Prix Jacques Le Marois at Deauville-La Touques Racecourse.

[9] Goldikova then returned to Santa Anita Park to win her second Breeders' Cup Mile, with a different racing style.

On 3 October, Goldikova made her final start before the Breeders' Cup Mile, defeating a field of 16 males in the Prix de la Forêt at Longchamp, including Dick Turpin, Paco Boy and 1,000 Guineas winner Special Duty.

[16] Goldikova made her six-year-old debut on 22 May by winning the Prix d'Ispahan for the second time, beating Champion Stakes winner Cirrus des Aigles.

[17] On 14 June Goldikova finished second by ¾ length to Canford Cliffs in the Queen Anne Stakes.

Goldikova won her 14th Group One, a European record, when winning her fourth consecutive Prix Rothschild at Deauville.

[18] On 15 August, Goldikova attempted to extend her top-level wins to 15 in the Prix Jacques Le Marois at Deauville, France.

On 4 November 2011, Goldikova finished third in the Breeders' Cup Mile, one length behind longshot Court Vision, who edged out Turallure by a nose.