Golemo Ilino (Macedonian: Големо Илино) is a village in the outskirts of the town of Demir Hisar within the municipality of Demir Hisar Municipality, Republic of North Macedonia.

in the 1467/1468 Ottoman defter, the village had 53 households and 3 bachelors.

A majority of household heads bore Slavic names, while around a quarter bore Albanian and mixed Slavic-Albanian ones.

The village was divided in two parts, the smaller of which would eventually become the settlement of Malo Ilino.

[1] In statistics gathered by Vasil Kanchov in 1900, the village of Golemo Ilino was inhabited by 640 Christian Bulgarians.