Gombasek Cave or Gombasecká jaskyňa (in Slovak) and Gombaszögi-barlang (in Hungarian) is a karst cave in the Slovak Karst, Slovakia.

It is named after the settlement of Gombasek, which belongs to the village of Slavec.

It is located in the Slovak Karst National Park, in the Slaná river valley, approximately 15 km south of Rožňava.

The cave was also used for "speleotherapy" as a sanatorium, focused on airway diseases.

Since 1995, the Gombasek Cave is included in the UNESCO World Heritage List as a part of the Caves of Aggtelek Karst and Slovak Karst site because of its exemplary speleothems and its record of karst formation under varying conditions, including periods of glaciation and temperate, and tropical climatic conditions.