Zandanshatar’s early career started as Lecturer in the College of trade and industry (1992–1995), after which he worked at the Agricultural Bank of Mongolia, progressively on different positions as Economist, Restructuring manager, Director of Forex department, Director of Loan and Monetary Policy department (1995–1998).

Zandanshatar actively worked to mobilize state support and attract foreign aid to the sector.

Other notable achievements during his tenure include strong anti-corruption measures taken against illegal privatization of large mining enterprises and a 50 percent improvement in air quality of Ulaanbaatar as a result of implementing smokeless fuel supply to households.

In 2019, his predecessor, Miyeegombyn Enkhbold, was ousted after numerous demonstrations by his political opponents, and Gombojavyn Zandanshatar was proposed and later elected unanimously by the Members of the Parliament as Chairman (Speaker).

Zandanshatar graduated from Baikal State University in 1992 (formerly Institute of National Economy in Soviet Union with a diploma of Specialist in Finance.

In 2014–2015 and 2016, Zandanshatar was a visiting scholar at the Center on Democracy, Development, and the Rule of Law at Stanford University in California.

He was impressed by the concept of deliberative polling developed by the center's director, James Fishkin, and translated his book on it, When the People Speak, into Mongolian.