The Gonō Line (五能線, Gonō-sen) is a railway line in Japan linking Higashi-Noshiro Station in Akita Prefecture with Kawabe Station in Aomori Prefecture, in the northern Tōhoku region of Honshu.

The line stretches 147.2 km (91.5 mi) along the Sea of Japan coast with a total of 43 stations.

The first section of the Gonō Line was opened by the Japanese Government Railways (JGR) from Higashi-Noshiro to Noshiro in 1908.

The private Mutsu Railway (陸奥鉄道, Mutsu-tetsudō) began operations on September 25, 1918 linking Kawabe with Goshogawara.

The company was nationalized in 1927, with the Goshogawara Line being absorbed into the Mutsu Railway.