[3] Khloé Alexandra Kardashian was born in Los Angeles, California on June 27, 1984[4] to Kris (née Houghton), a homemaker, and Robert, an attorney.

[5] Their mother is of Dutch, English, Irish and Scottish ancestry,[6][self-published source] while their father was a third-generation Armenian American.

[7] After her parents divorced in 1991,[8] her mother married 1976 Summer Olympics decathlon winner Caitlyn Jenner (then Bruce)[c] in 1991.

[10] Through their marriage, Kardashian gained stepbrothers Burt, Brandon, and Brody; stepsister Casey; and half-sisters Kendall and Kylie.

[11] In 1994, her father garnered public attention as a defense lawyer for football player O. J. Simpson during his murder trial.

[16][17] Later that year, Khloé; her mother Kris; her stepparent Caitlyn; her siblings Kourtney, Kim, and Rob; and half-sisters Kendall and Kylie were commissioned to star in the reality television series Keeping Up with the Kardashians.

[19] In April 2009, Kardashian and her sister Kourtney announced that they were contracted to star in a spin-off that would follow their move to launch a D-A-S-H store in Miami, Florida.

[20] Starting May 29, 2009, Kardashian joined Miami Top 40 Mainstream outlet WHYI for a weekly four-hour talk/entertainment program, co-hosted by 106 & Park's Terrence J.

In June 2009, Khloé and her sisters teamed up with the Natural Products Association to create a teeth whitening pen called Idol White.

In October 2012, Kardashian and Odom released a second unisex fragrance, "Unbreakable Joy," inspired by the holiday season.

[35] She later made an appearance on the MTV television series Punk'd with Kelly Osbourne and Miley Cyrus in February 2012.

In January 2016, Kardashian hosted the Kocktails with Khloé pop culture–themed variety talk show, which aired on the FYI cable channel.

[38] Kardashian and business woman Emma Grede launched their clothing line Good American in the same year, and made $1 million in sales on the first day.

In December 2018, Kardashian became the brand ambassador of Burst Oral Care & performed corn test on the electric toothbrush.

This marked their third collaboration, after previously launched special collection of lip products called Koko Kollection in 2016 and the second part in 2017.

[51][52][53] The show features Kardashian, alongside her sisters Kourtney, Kim, Kendall and Kylie, and mother Kris Jenner, it also features ex and current partners including Scott Disick, Travis Barker, Kardashian's ex Tristan Thompson, and Corey Gamble, with Kanye West making a guest appearance.

[65] Kardashian's physique, notably her face, has attracted significant attention from the media and public in recent years.

Luckily, I have been vaccinated so all will be ok."[70] In October 2022, Kardashian revealed she had had a "rare" tumor removed from her face, having initially assumed it to be a zit.

[72] On September 27, 2009, Kardashian married professional basketball player Lamar Odom, who was a member of the Los Angeles Lakers at the time.

[78] On December 13, 2013, after months of speculated separation, Kardashian filed for divorce from Odom and for legal restoration of her last name.

[80][81][82] The divorce had yet to receive final approval from a judge[83][84] in October 2015, when Odom was hospitalized after being found unconscious in a Nevada brothel.

[85][86] In an interview with People Magazine, Kardashian confirmed that they had not reconciled, but the divorce had been withdrawn so that she could make medical decisions on Odom's behalf.

[89][90] Kardashian started dating basketball player James Harden after meeting at brother-in-law Kanye West's Staples Center birthday party in 2015.

[104][101] Kardashian supports the recognition of the Armenian genocide and has visited Tsitsernakaberd, the memorial to the victims in Yerevan, Armenia.

[108] In October 2020, Kardashian spoke out in support of Republic of Artsakh and Armenians, condemning Azerbaijan's involvement in the 2020 Nagorno-Karabakh conflict.

[109] On October 10, 2020, she spoke on the ArmeniaFund fundraising telethon and urged viewers to donate money to help those impacted by the recent war.

[111] In April 2015, she was named godmother of her niece North West, by Kim and Kanye, as the child was baptized in the Armenian Apostolic Church at the Cathedral of St. James in Jerusalem.

[115][116][117] In March 2012, Kardashian and her sisters Kourtney and Kim were named in a $5 million class-action lawsuit against QuickTrim, the weight-loss supplement they endorse.