[4] Čomić appeared on the Democratic Party's electoral lists for the Novi Sad division in the 1992 and 1993 Serbian parliamentary elections, although she did not receive an assembly mandate on either occasion.

)[6][7][8] The DS contested the 1996 Yugoslavian parliamentary election as part of the Zajedno (English: Together) coalition, and Čomić appeared in the lead position on its electoral list for Zrenjanin.

[11] The Socialist Party of Serbia (SPS) won a majority victory at the provincial level, and Čomić led the Zajedno opposition group in the assembly from 1997 to 2000.

Čomić was re-elected for Novi Sad's tenth division in the 2000 Vojvodina provincial election, which took place concurrently with the presidential vote.

[16] The list won a landslide majority victory with 176 out of 250 mandates, and she was included in the DS's delegation when the new assembly convened in January 2001.

The Democratic Party contested the resulting 2003 parliamentary election at the head of its own alliance, and Čomić received the sixth position on its electoral list.

[21] The rival Democratic Party of Serbia (DSS) formed a coalition government after the election, and the DS moved into opposition.

[25] In 2006, she was appointed as part of Serbia's delegation to the Parliamentary Assembly of the Organization for Security and Co-operation in Europe (OSCE PA).

[26] She supported Serbia's integration into the European Union and criticized what she regarded as efforts to increase the country's dependence on Russia.

[29][30] The DS formed an unstable coalition government with the DSS and G17 Plus after the election, and Čomić served as part of its assembly majority.

[36] Serbia's electoral system was again reformed in 2011, such that all parliamentary mandates were awarded to candidates on successful lists in numerical order.

Čomić continued to serve as part of Serbia's delegation to the OSCE PA and was selected by that body as a rapporteur for human rights and migration.

[52] The Democratic Party began boycotting the national assembly in early 2019, against the backdrop of significant public protests against Serbia's government.

She defended her decision on the grounds that her purpose was to present draft legislation requiring at least forty per cent female representation on election lists at the republican and municipal levels.

Shortly after Čomić returned to the assembly, she took part in a press conference with representatives of the Serbia 21 party, who announced that they would participate in the 2020 parliamentary election despite broader calls for an opposition boycott.

Čomić sought to downplay the importance of Vučić's opposition, saying that the law's validity would ultimately be determined by Serbia's constitutional court.

[64] After the 2022 Serbian parliamentary election (in which she was not a candidate), she indicated that the draft law had been completed with the help of expert opinion from the Council of Europe and that it was ready for the mandate of Serbia's incoming government.