[4] The college is located on the east bank of Kham river in northwest part of Aurangabad city, very close to famous tourist attractions like Panchakki, Bibi Ka Maqbara and Dr. Babasaheb Ambedkar Marathwada University.

The foundation stone for the present main building of the medical college was laid down by then chief minister of Bombay State, Yashwantrao Chavan, in presence of Swami Ramanand Teerth, on 27 October 1957.

The building was inaugurated by Sushila Nayyar, then Minister of Health, Government of India, on 20 June 1964.

The PSM department also operates one urban healthcare centre in the Shahganj area of Aurangabad.

Faculty and students of the GMCH have their research papers published in number of national and international journals.

[13][14][15][16][17][18] Sandfly fever, an aroboviral disease is known to occur in the arid regions of West Pakistan and Middle East.

[19] The GMC provides residential facility for all its faculty members, staff and students inside the campus.