The first governor of Maynas was Diego Vaca de Vega [es], who in 1619 obtained the authorization and assistance necessary for the formation of a new government from the Real Audiencia of Quito.

It is assumed that these sites of the Pajonales are near the junction of the Jauja with the Apurímac, from where it is called Ucayali, at 11 degrees of southern altitude.Based on the conformity of the facts of the conquest of the missionaries of Quito, the governorate extended over the Ucayali River to the area occupied by the nations of the Campas (or Cambas) Indians, that is, bathed by the Paucartambo, Santa Anna, Urubamba, Apurimac and Jauja, that is, up to the boundaries of the Real Audiencia of Charcas, today Bolivia.

In 1685 Father Samuel Fritz, who was one of the Quito Jesuits of German origin, had spread throughout the Amazon to near the mouths of the Atlantic Ocean; but he was stripped of his Great Omagua Missions by the Portuguese.

In the context of the difficulties in sending religious to the Marañón and the pressures to repatriate them to Europe, the decision was made to intervene from the Court of Madrid.

Despite the adversities, in September 1684, Father Manuel Rodríguez assigned seven Jesuits to Quito, among whom Juan Gastel of Austria, Samuel Fritz and Enrique Richter of Bohemia stood out.

The Royal Decree of September 2, 1772 provided: [...that] those currently serving cease the exercise of the three Governments of Borja, Quijos and Macas, subrogating themselves to those that I (the King) will appoint [...] whose Governors will be responsible for corresponding with each other, reciprocally communicating everything what was offered to them and seemed important to that end.

Regarding the expulsion, there is testimony about the journey and the adventures that the Jesuits had to endure towards Europe, especially those who were in the missions, such as that documented through a letter from missionary Javier Crespo to Spanish functionary José Diguja [es].