It was established in 1933 as MAO College by Anjuman-e-Islamia at Amritsar and Professor S. Mercado was appointed the first principal.

), Chemistry, English, Physics, Mathematics, Mass Communication, Philosophy, Psychology, Statistics, and Social Work.

Physics, Psychology, English, Mathematics, I.T., Mass Communication, and BS Chemistry degrees at the undergraduate level, and the Master of Arts (M.A.)

College Lahore provides BS Honors (4-Year) co-education program at the undergraduate level.

However, last Principal Prof. Rashid Najeeb took the responsibility and it was due to his efforts that “IQRA” was published again in 2014.

MAO College is also well known[citation needed] for co-curricular, extracurricular, and sports activities.

The college's alumni include many national players like Saeed Ajmal, Saqlain Mushtaq, Taufeeq Umar, and Salman Akbar.

College made headlines when its first female principal, Dr. Aaliya Rehman Khan, was seen riding her bicycle to and from M.A.O.

Her act aimed to educate students about the detrimental effects of carbon emissions on the environment while also promoting healthy lifestyles.