Grêmio Foot-Ball Santanense, commonly known as Grêmio Santanense, is a Brazilian football club based in Santana do Livramento, Rio Grande do Sul and part of the state league competition in the state of Rio Grande do Sul.

The club was founded on June 11, 1913,[1] adopting Grêmio's name and Internacional's colors.

Grêmio Santanense also won the Campeonato do Interior Gaúcho in 1937 and in 1948.

Grêmio Foot-Ball Santanense play their home games at Estádio Honório Nunes.

[1] The stadium has a maximum capacity of 8,000 people.