Grafenau (German pronunciation: [ɡʁaːfəˈnaʊ̯] ⓘ) is a town in the Freyung-Grafenau district, in Bavaria, Germany.

The Kleine Ohe river flows along the east and south of the town.

In April 1945, Major General Stafford LeRoy Irwin opened his XII Corps Headquarters there.

The town has curling and ice skating rinks (which are seasonal), and ski drag lifts in an area which in summer months is used for bobsleds.

There is a Catholic church, a railway terminus, and a bus station, in addition to a range of hotels, shops, and garage facilities for motorists.