Annable has created works for the television, film, video game, and comic book industries.

[1] After graduating from Sheridan College in Oakville, Ontario, where he was classically trained as an animator,[2] Annable ended up at LucasArts.

He worked there for ten years, starting in 1994 on Full Throttle and ultimately as a lead animator on the cancelled Sam & Max: Freelance Police.

[3][4] In addition, Annable has done illustration and cartoon work for (among others) Chuck Jones, Nickelodeon, and Walt Disney Productions.

Annable was employed as creative director at Telltale Games during their first year, and has continued working closely with them, later designing Puzzle Agent, amongst other titles.