[3] Gramercy was originally an American Indian and French settlement and trading post.

In 1739, much of the area which is now known as Gramercy was sold to Joseph Delille Dupart, Commissioner of Indian Nations under Jean-Baptiste Le Moyne de Bienville.

As of the 2020 United States census, there were 2,932 people, 1,177 households, and 954 families residing in the town.

At the 2000 United States census,[13] there were 3,066 people, 1,090 households, and 833 families residing in the town.

Gramercy was the home of Zapp's Potato Chips and Louisiana Sugar Refining, LLC (LSR).

[14] LSR operates a state-of-the-art sugar refinery with a capacity of 3,100 tons per day.

[15] LSR is located in the Colonial Sugars National Historic District.