Its full title, the Grammaire égyptienne ou Principes généraux de l'écriture sacrée égyptienne appliqué à la présentation de la langue parlée means Egyptian Grammar or General Principles of Egyptian Sacred Writing Applied to the Presentation of the Spoken Language.

Upon his return from Egypt to France on 5 March 1830, after almost twenty months of absence, Champollion immediately gave priority to the clarification of his Grammaire.

Marcellin Jobard, a lithographer from Brussels, whom claimed to have advised Champollion the use of lithography for the printing of the Grammaire égyptienne.

Grammaire points out that the Egyptian hieroglyphs are a complex system, writing figurative, symbolic, and phonetic all at once.

Émile Prisse d'Avennes, a French engineer, became Egyptologist after studying Grammaire égyptienne.